RTTPG

Gene Name : POLE

Synonym : POLE1

Ensembl Gene ID : ENSG00000177084

Protein Class : Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Human disease related genes, Metabolic proteins, Plasma proteins, Predicted intracellular proteins

Gene Description : DNA polymerase epsilon, catalytic subunit

Molecular Function : DNA-binding, DNA-directed DNA polymerase, Hydrolase, Nucleotidyltransferase, Transferase

Disease Involvement : Cancer-related genes, Disease variant, FDA approved drug targets

Tissue count: Brain_Cerebellar Hemisphere : 5 / 22, Brain_Cerebellum : 10 / 22, Skin_Sun Exposed (Lower leg) : 1 / 22, Spleen : 1 / 22, Testis : 15 / 22,

TREGT

Rank	Transcript ID	Transcript Length	ORF Length	Transcript TPM	Z-Score ≥ 3 Count	Z-Score ≥ 3 Tissue1	Z-Score ≥ 3 Tissue2	Z-Score ≥ 3 Tissue3
1	ENST00000541627	2105		6.576311007	3	Brain_Cerebellar Hemisphere	Brain_Cerebellum	Testis
2	ENST00000320574	7840	6861	5.898412203	2	Brain_Cerebellum	Testis
3	ENST00000434528	808		2.432582355	1	Testis
4	ENST00000544870	659	451	1.111767579	3	Brain_Cerebellar Hemisphere	Brain_Cerebellum	Testis
5	ENST00000537064	8011	933	0.933227307	2	Brain_Cerebellar Hemisphere	Brain_Cerebellum
6	ENST00000542362	508		0.868026245	1	Testis
7	ENST00000538196	551		0.833526964	1	Testis
8	ENST00000545015	366		0.668499359	1	Testis
9	ENST00000544414	575		0.612215884	1	Testis
10	ENST00000539215	483		0.462052605	2	Brain_Cerebellar Hemisphere	Brain_Cerebellum
11	ENST00000441786	556	464	0.302396681	1	Testis
12	ENST00000536445	2334		0.298206707	2	Brain_Cerebellum	Testis
13	ENST00000534922	1660		0.189107118	2	Spleen	Testis
14	ENST00000540987	587		0.178792714	0
15	ENST00000539357	364		0.177536371	0
16	ENST00000544692	2221		0.168572701	2	Brain_Cerebellum	Testis
17	ENST00000416953	542		0.106951013	3	Brain_Cerebellar Hemisphere	Brain_Cerebellum	Testis
18	ENST00000539618	299		0.084138568	1	Skin_Sun Exposed (Lower leg)
19	ENST00000541213	1675		0.072456033	2	Brain_Cerebellum	Testis
20	ENST00000503265	1501		0.060115329	2	Brain_Cerebellum	Testis
21	ENST00000535934	1561		0.049361977	0
22	ENST00000535270	6800	6780	0.001129977	0

TPM Log10 Z-Score